Olaparib Impurity 155 CAS 763111-46-2(free base)
| CAS No. | 763111-46-2(free base) |
| Molecular Formula | C20H20N4O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 384.86 g/mol gives Olaparib Impurity 155 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Olaparib Impurity 155 (CAS 763111-46-2(free base)) is a certified pharmaceutical impurity reference standard with the molecular formula C20H20N4O2HCl and a molecular weight of 384.86 g/mol.
Based on its molecular formula C20H20N4O2HCl, Olaparib Impurity 155 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 384.86 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Olaparib Impurity 155 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H20N4O2 HCl |
| Molecular Weight | 384.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Olaparib Standards
- Olaparib Impurity 69 (CAS 1007-16-5)
- Olaparib Impurity 24 (CAS 1021298-67-8)
- Olaparib Impurity 12 (CAS 1021298-68-9)
- Olaparib Impurity 88 (CAS 1062292-60-7)
- Olaparib Impurity 28 (CAS 1187479-72-6)
- Olaparib Impurity 134 (CAS 134435-16-8)
- Olaparib Impurity 93 (CAS 1379332-00-9)
- Olaparib Impurity 79 (CAS 13889-98-0)
Recommended Standards
- Pramipexole Impurity 48 (CAS CATO-C4X-110748)
- Miglitol Impurity A (CAS 1370331-33-1)
- Pyridoxine Impurity 78 (CAS CATO-C4X-187778)
- Baricitinib Impurity 51 (CAS CATO-C4X-226051)
- 3-Oxo-2,3-dihydro-1h-indazole-4-carboxylic acid (CAS 7384-17-0)
- 2-[5-Methyl-3-(4-methylphenyl)-7-oxo-7H-furo[3,2-g]chromen-6-yl]acetic acid (CAS 853892-67-8)
- 2-Fluoro-6-iodoisonicotinamide (CAS 1803811-90-6)
- 3-(1-methylpyrrolidin-2-yl)propanoic acid hydrochloride (CAS 18325-19-4)
- Polydatin (CAS 27208-80-6)
- Tirzepatide Impurity 43 (CAS CATO-C4X-324043)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com